2016 Annual Report for the year ended June 30 2016
22 December 2016
The Banting Research Foundation and the Rick Hansen Institute are pleased to announce a funding partnership to support research by early career investigators focused on areas relevant to spinal cord injury (SCI).
The human and economic costs of SCI are devastating. For the 86,000 Canadians who have spinal cord injuries, life is changed forever. SCI costs the Canadian economy more than $2.7 Billion annually, in health care costs and lost productivity.
The Banting Research Foundation/ Rick Hansen Institute Discovery Award is a one-year grant of up to $25,000 that will support research which could potentially enable medical breakthroughs and transformative health care advances to reduce the human and economic costs associated with SCI. Eligible candidates must be focused on research in one or more of the following areas relevant to SCI: paralysis, pressure ulcers, urinary tract infections, neuropathic pain, predictive preclinical models of evaluation, and spinal cord injury in Indigenous Peoples in Canada. Eligibility is not limited to those specializing in the field of SCI, but the research must be applicable to SCI. The Banting Research Foundation/ Rick Hansen Institute Discovery Award will be awarded through the grant program of the Banting Research Foundation.
Eligible applicants must be in the first three years of an academic appointment at a university or research institute in Canada. For complete guidelines and application instructions, see: bantingresearchfoundation.ca/grants/guidelines/
Application deadline: March 15, 2017 READ THE WHOLE STORY »
16 December 2016
The Banting Research Foundation sponsored the 2016 Friesen Prize program, where Dr Janet Rossant was awarded the Henry G Friesen International Prize in Health Research. READ THE WHOLE STORY »
13 December 2016
The Banting Research Foundation awarded 16 prizes for top oral abstracts and posters at the Young Investigators Forum at the 2016 annual meetings of the Canadian Society for Clinical Investigation (CSCI) and the Clinician Investigator Trainee Association of Canada (CITAC). READ THE WHOLE STORY »
30 September 2016
In September 2016, the Banting Research Foundation welcomed 60 guests to a celebration of Banting’s Legacy, the Art and Science of Discovery. Frederick Banting’s accomplishments as a scientist and an artist inspired the theme for the evening. READ THE WHOLE STORY »
26 August 2016
Tara Moriarty PhD and PhD student Rhodaba Ebady at the University of Toronto have developed an imaging system that is able to show how bacterial cells move through blood vessels to infect other parts of the body. Using the bacteria that causes Lyme disease, Borrelia burgdorferi, they showed how bacterial cells attach themselves to the inner surface of blood vessels with tether-like structures, grabbing and releasing to move themselves along without being swept away by the forces of blood flow. Knowing the mechanism of this movement is a critical step in the development of therapeutics to treat Lyme disease and other similar infections. READ THE WHOLE STORY »
26 July 2016
Department of Microbiology and Immunology, Dalhousie University
Directing natural killer cell cytotoxicity to the tumour’s susceptibilities
26 July 2016
Department of Mechanical Engineering, University of Alberta
Impact severity metric for focal head and diffuse brain injury
Whether or not today’s helmets protect the wearer from mild diffuse brain injuries, sometimes referred to as concussions, is the topic of intense debate. One of the primary venues for this debate is in the helmet standards and certification community. READ THE WHOLE STORY »
26 July 2016
Department of Biology, Laurentian University
Investigating the role of H2S in the regulation of ghrelin secretion
Ghrelin, a hormone produced in the endocrine cells of the stomach, regulates several aspects of metabolic health, including appetite and energy storage. Recently, meals high in the amino acid cysteine have been shown to reduce ghrelin secretion. Foods rich in this amino acid also lead to increased production of the bioactive gas molecule hydrogen sulfide (H2S). H2S has been shown to regulate many aspects of health, including inflammation, cardiovascular health, and endocrine control. Dr Gagnon believes that ghrelin cells can metabolize cysteine to produce their own H2S, and that this H2S reduces ghrelin secretion and reduces appetite. He will first demonstrate how H2S and its precursor amino acid L-cysteine can regulate ghrelin secretion using several ghrelin producing cell models. He will then examine how this amino acid, and its gas metabolite, can suppress food intake through the suppression of ghrelin. This work will provide important information on how ghrelin and appetite is regulated by H2S and may lead to new strategies in weight management.
26 July 2016
Department of Psychology, University of Guelph
Evaluating novel neurobiomarkers in the identification of adults with FASD using portable eye tracking and EEG technology
Individuals with fetal alcohol spectrum disorder (FASD) are overrepresented in the criminal justice system. There is an urgent need to identify neurobiomarkers of FASD and individuals at risk in order to reduce recidivism and the resulting high social, health, and economic costs. Novel use of neurotechnologies, including portable eye movement control tracking and EEG, may offer a window into the brain and aid in the identification of patterns of deficits in offenders with FASD. READ THE WHOLE STORY »
26 July 2016
Department of Psychology, Wilfrid Laurier University
Exploring neural mechanisms of social behavior using zebrafish (Danio rerio)
This research study uses zebrafish, a small freshwater species of fish commonly used in genetic and developmental research, to explore the mechanisms of social behavior. Zebrafish spend the majority of their time in groups and have complex social interactions, including learning from each other, making collective decisions about where to search for food, and communicating about the presence of predators. READ THE WHOLE STORY »
26 July 2016
Department of Medicine, Université Laval
Targeting ErbB2 by TAK-165 reverses pulmonary hypertension in vitro and in vivo
In pulmonary hypertension (high blood pressure in the lungs), cells forming the walls of arteries in the lungs proliferate like cancer cells, narrowing the arteries and making it difficult for blood to pass through. There is also evidence of inflammation, similar to that in infections, and evidence of insulin resistance, as in diabetes. READ THE WHOLE STORY »
30 June 2016
Congratulations to the Banting Research Foundation 2016 Discovery Award recipients. Six grants were funded in the 2016 competition out of 50 applications. The successful Discovery Award recipients are:
16 May 2016
Dr Janet Rossant was invested into the Order of Canada in a ceremony at Rideau Hall on May 13, 2016. She was appointed in May 2015 to the rank of Companion of the Order of Canada, the highest level within the Order, for advancing the global understanding of embryo development and stem cell biology, and for her national and international leadership in health science.
Earlier in 2016, Dr Rossant was awarded the 2016 Henry G. Friesen International Prize in Health Research, and in 2015, received the prestigious Canada Gairdner Wightman Award for her outstanding scientific contributions to developmental biology and for her exceptional international leadership in stem cell biology and policy-making, and in advancing research programs for children’s illnesses.
Dr Rossant is internationally renowned as a developmental biologist, known for her studies of the genes that control embryonic development. Originally from the UK, she came to Canada in 1977 to assume a faculty position at Brock University. She moved to the University of Toronto in 1985, at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital and then at the Hospital for Sick Children, where she was Chief of Research.
While an assistant professor at Brock University in 1983, Dr Rossant received a grant from the Banting Research Foundation for her early research in developmental biology. She says, “the early support of the Banting Research Foundation was very helpful in setting my course towards the Gairdner Wightman Award.”
19 January 2016
Following Sir Paul Nurse’s December 7, 2015 Friesen Prize Lecture at the University of Ottawa entitled “The Fundamental Significance of Discovery Science in the Creative Process,” distinguished leaders in health science and education gathered for Roundtable Discussions concerning the roles of discovery research of graduate science education in the health of Canadians, co-sponsored by the Banting Research Foundation, the Royal Canadian Institute for Science and Friends of CIHR.
The proceeding of the Policy Roundtables from the 2015 Friesen Prize Program are available here (19MB):