1 August 2011

Marcelo Berlim, MD, MSc

Department of Psychiatry, McGill University

Remediating decision-making deficits in depressed subjects at high risk for suicide with transcranial magnetic stimulation

We aim to assess whether high frequency repetitive transcranial magnetic stimulation, a safe and non-invasive method for modulating the activity of specific brain regions, when applied over the left region of the forehead (ie, the orbitofrontal cortex) of depressed subjects at high risk for suicide is able to improve decision-making deficits which may predispose these subjects to suicidal behavior. READ THE WHOLE STORY »

1 August 2011

Simon J Lees, PhD

Faculty of Medicine, Lakehead University

The IL-6 paradox in the development of insulin resistance

Paradoxically, elevated IL-6 is associated with insulin resistance and type 2 diabetes, while at the same time strong evidence supports the notion that IL-6 may facilitate improved insulin signaling as a result of physical activity. READ THE WHOLE STORY »

1 August 2011

Tara Moriarty, PhD

Matrix Dynamics Group, Faculty of Dentistry, University of Toronto

Vascular adhesion mechanisms of the Lyme disease spirochete

Blood-borne spread (dissemination) of pathogens is a critical step in the development of serious infectious disease, and is responsible for most of the mortality due to bacterial infection. The dissemination mechanisms of many bacterial pathogens are largely unknown. READ THE WHOLE STORY »

1 August 2011

Takako Niikura, DVM, PhD

Faculty of Health Sciences, Simon Fraser University

Regulation of amyloid beta metabolism

In Alzheimer’s disease (AD), progressive brain atrophy and dementia appear because of neuronal cell death and synaptic dysfunction in brains. Amyloid beta plays a central toxic role in AD pathogenesis. READ THE WHOLE STORY »

1 August 2011

Jonathan Perreault, PhD

INRS – Institut Armand Frappier

Regulation in the opportunistic pathogen Burkholderia by the MAEB RNA motif

Aside from their role in storing hereditary information, DNA and RNA are now known to have many more functions. Living organisms have a plethora of RNAs that control numerous processes in cells. One such RNA, named MAEB, was recently found by computer-aided searches in the opportunistic pathogen¬†Burkholderia. READ THE WHOLE STORY »

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Founded in 1925 by supporters of Frederick Banting,
1923 Nobel laureate for the discovery of insulin

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