CRCHUM, Department of Medicine, Université de Montréal Evaluating the therapeutic potential of 14-3-3ζ for the treatment of obesity Approximately 25% of Canadians are either overweight or obese. Current therapies have only modest success in reducing body weight, and surprisingly, none directly target fat cells, which are key in the development of obesity.
Catherine Larochelle, MD PhD
CRCHUM, Department of Neurosciences, Université de Montréal Molecular mechanisms underlying T lymphocytes interactions with oligodendrocytes in neuroinflammation In multiple sclerosis (MS), there is an abnormal response of immune cells against cells of the brain and spinal cord. Oligodendrocytes, the myelin-producing cells that support and insulate neurons, are injured by the inflammatory response, leaving neurons vulnerable.…
Catherine Martel, PhD
Department of Medicine, Université de Montréal/ Montreal Heart Institute Research Centre Lymphatic vessel function in atherosclerosis High blood cholesterol is an important risk factor for cardiovascular diseases such as atherosclerosis. High-density lipoprotein (HDL) is called “good cholesterol” because it transports cholesterol away from tissues, such as the blood vessel walls, carrying cholesterol through the blood…
