Department of BiochemistryUniversité de Sherbrooke Deciphering the epigenetic regulation of alternative splicing in neurons Aging can reduce the birth of new neurons, a process called neurogenesis. The challenge is to prevent our neurons from dying in old age and keep growing new ones in order to stave off neurodegenerative diseases. Dr. Laurent’s research project aims…
Florian Bentzinger, PhD
Department of Pharmacology-Physiology, Université de Sherbrooke Niche regulation of muscle stem cell specification Dr Bentzinger’s group studies the role of regulatory signals in the microenvironment where skeletal muscle stem cells (MuSCs) reside. Understanding how this so-called “stem cell niche” controls MuSCs and how these instructive mechanisms become disrupted in aging and disease, could help in…
Jeffrey Leyton, PhD
Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke An advanced development in targeted radiation against muscle invasive migrating bladder cancer cells Bladder cancer affects thousands of Canadians on an annual basis. Unfortunately, bladder cancer remains one of the most difficult cancers to manage. The treatment options currently available to patients with muscle invasive bladder…
Michelle Scott, PhD
Department of Biochemistry, Université de Sherbrooke Characterization of a novel function of small RNAs in alternative splicing The process of alternative splicing allows the production of multiple distinct proteins from a single gene, in a manner that can be cell-type specific. Alternative splicing requires an extensive and complex regulation. Diverse human diseases can be caused…
